PDL1 shapes the classical Hodgkin lymphoma microenvironment without inducing T-cell exhaustion
Classical Hodgkin lymphoma (CHL) is unusually sensitive to PD1 inhibition and PDL1 is highly expressed on CHL cells and in the tumor microenvironment.This could be 2007 pontiac grand prix exhaust system interpreted as evidence of exhaustion, but paradoxically, PD1+ lymphocyte infiltration does not predict response to PD1 inhibitors and no increase